Goal: To guage the clinicopathological traits of foot and ankle gentle tissue and bone tumor, and to investigate the prognosis and the associated components of malignant tumors on this web site.

Strategies: 74 sufferers with gentle tissue and bone tumors of foot and ankle from January 2006 to February 2017 had been retrospectively analyzed. The clinicopathological traits, the remedy and survival standing of malignant tumors had been adopted up, and the medical and therapeutic components associated to prognosis had been analyzed.

Outcomes: Of the 74 sufferers, 34 had been males and 40 had been females. The male to feminine ratio was 1∶1.18; the age ranged from 12 to 64 years and the median age was 42 years. Tumors positioned in forefoot of twenty-two instances, 22 in midfoot, 10 in hind foot, 14 in ankle joint and 6 in a number of websites. 14 instances had been bone tumors, together with 7 benign and seven malignant, and 60 instances had been gentle tissue tumors, together with 14 benign and 46 malignant. The commonest malignant gentle tissue tumors had been synovial sarcomas (13 instances), and the commonest benign gentle tissue tumors had been hemangiomas (4 instances). 44 instances of malignant tumors underwent surgical procedure had been adopted up, of which had been 7 bone and 37 gentle tissue malignant tumors. Limb salvage surgical procedures had been carried out in 33 instances and amputation in 11 instances. The median follow-up time was 69.8 months, and the median survival time was 40.7 months. The 1-year, 3-year and 5-year survival charge of soppy tissue malignant tumors was 88.0%, 73.0%, and 63.0%, respectively. The 1-year, 3-year and 5-year survival charge of bone malignant tumors was 86.0%, 57.0% and 57.0%, respectively. Univariate evaluation confirmed that the prognostic components affecting 5-year survival charge had been tumor measurement and adjuvant remedy (P<0.05). Affected person’s gender, age, tumor location, histological sort and surgical process had no impact on general survival(P>0.05). Multivariate evaluation confirmed that tumor measurement was an impartial prognostic issue (RR=7.262, P=0.005).

Conclusions: Forefoot and midfoot are extra frequent in foot and ankle gentle tissue and bone tumors. Synovial sarcoma is the commonest prognosis in malignant gentle tissue tumors, and hemangioma is the commonest prognosis in benign gentle tissue tumors. The prognostic issue of malignant gentle tissue and bone tumors in foot and ankle is tumor measurement. Sufferers with the tumor measurement of 5 cm or extra have a worse prognosis.